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Wed, Feb 14


Kemomed, Izobraževalni center

BioLC: Analysis of biological drugs

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BioLC: Analysis of biological drugs
BioLC: Analysis of biological drugs

Time & Location

Feb 14, 2024, 12:00 PM – 4:00 PM

Kemomed, Izobraževalni center, Brnčičeva ul. 31, 1231 Ljubljana - Črnuče, Slovenia

About the Event

Dear Participants,

you are invited to join us at the BioLC: Analysis of biological drugs seminar.


12.00-13.00, Lunch and registration of participants

13.00-13.10, Wellcome and introduction

13.10-14.15, Introduction to Biopharma world

•             Introduction and terminology

•             Biosimilar vs ADC

•             Critical Quality Attributes

Separative modes, stationary phases, and Bio hardware

•             Matrices of (U)HPLC Columns: main characteristics

•             Differences between Bio-inert and Bio-compatible

•             The separative modes:

o             RP

o             SEC

14.15 – 14.30 Break

14.30 – 16.00 Main workflows for the characterization of biological drugs

•             RP approaches for protein characterization (Intact Vs Peptide)

•             SEC Chromatography:

o             Aggregation Studies of Therapeutic Protein

o             Mechanism and method development

•             Analysis and characterization of Oligonucleotides

o             The LC and MS effects of ion pair

o             The optimization of the mobile phase

o             The role of SPE in the purification and analysis of oligo

Welcome to join the seminar!

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