Chromatographic Considerations for Native and Denaturing ESI for Large Molecule Characterization

Intact mass is a common workflow for the analysis of large molecules by high-resolution MS. It can be useful for the identification of primary sequence, as well as the characterization of different isoforms. Intact mass can be divided into two different approaches.

Chromatographic Considerations for Native and Denaturing ESI for Large Molecule Characterization